The Mind-Body Connection and You

There is now both reliable and valid scientific evidence from the fields of behavioral medicine, neuroendocrinology, neuroimmunology, neurobiology, and nutrition science to support the conclusions that our autonomic, endocrine and immune systems are not autonomous, but instead work in concert with each other.  These systems engage in interactive dialog with each other, and communicate with our limbic emotional system and perception/sensation systems to maintain health and also fight disease.

Research over the past 30 years has seen considerable advances into the scientific understanding of the immune system.  Science has now established the knowledge that the mind (psychology), the brain (neurology) and the body’s natural defenses (immunology) communicate with each other in a bidirectional flow of hormones, neuropeptides and cytokines.  This growing field of research is called psychoneuroimmunology (PNI).     Consider this: there is now irrefutable evidence that all of the body’s defense systems are under the control of the central nervous system (CNS).   In other words, every idea, thought and belief has a neurochemical consequence.  Neuropeptides flow from the CNS, impinging on specific receptions on the leukocytes, thus regulating their function.  What researchers know then, is that the CNS has the potential to critically inhibit or enhance immunity through two major neuroimmunomodulatory pathways:  the neuroendocrine and the autonomic nervous systems.

What can you do as a patient, whether you are struggling with a chronic illness, newly diagnosed with a threatening disease or health and working toward goals to improve your overall health and well-being?

Begin by examining your stress levels. How do you manage?  Do you feel good about how you cope or do you know that you are frequently stressed beyond your ability to cope? Ask for help.   Examine your health beliefs and ask questions of your health care providers.  Ask for psychological support for stress management, or help with depression, anxiety or other diagnosis.  Read and learn all you can about the biopsychosocial aspects of your condition.  Rely on scientific evidence, scientific based websites and reputable publications.  Question and learn about complimentary and adjunct support and discuss with your health care providers, including your medical doctor and your psychologist.
For an excellent academic overview on this topic:  Mind-Body Medicine: A Clinician's Guide to Psychoneuroimmunology; edited by Dr. Alan Watkins ISBN:  0 443 05526 2

Related articles

• Some depression might have roots in immune-generated inflammation (scientificamerican.com)

Do women respond differently to stress than men?

Shelly C. Taylor, a recognized psychologist and researcher at UCLA, investigated  women’responses to stress and how those responses may be different from the accepted “fight or flight” theory I discussed in an earlier article.  The results from Taylor’s study demonstrated that the neuropeptide called oxytocin, (which also plays a roll in sexual arousal, monogamous bonding, childbirth, maternal bonding to the newborn, among other primarily female responses) also plays a role in the stress response.  Taylor provides support for identifying oxytocin as a ‘social thermostat.’  As a social thermostat, oxytocin informs the brain on whether social resources are adequate to deal with stressful events.  Based on the study, Taylor suggests that oxytocin then, may be a biological marker, with higher levels of oxytocin indicating inadequate or depleted social connection and support.  If you want to read and learn more about your own stress style and how to uniquely and proactively manage your stress response, I highly recommend the book “So Stressed,” by Stephanie McClellan, M.D. and Beth Hamilton, M.D. (ISBN #9781416593584)  They present an excellent guide to stress, how stress uniquely effects women, four types of stress profiles, and what women can do to uniquely and proactively  counter stress and become psychologically and physiologically healthier. So then, do women respond differently to stress than men?  Yes, there are definite differences, one of them, based on Taylor’s work is to tend and befriend, reaching out to others and seeking support when it is needed.

Are you a Victim?

When you experience a health crisis – whether it’s being newly diagnosed with a disease, experiencing overwhelming stress from dealing with a chronic disability or recovering from an injury, feeling angry may be a normal response.  However, ongoing anger is not a healthy response to the stressor and may keep you from healthy management and feeling better in the long run.   Chronic anger may add to your stress levels, increase the cortisol in your system, which in turn contributes to more inflammation and poorer health. The key is to learn and then act on the knowledge that there are normal and healthy anger responses and there are also unhealthy anger responses.

In addition to denial, what is another common and unhealthy anger response? In addition to denial, which I discussed last week, is a type of anger response that involves seeing yourself as victim of your circumstances, your disease, and even your overall health status. Taking on a role as 'victim' may not seem like an anger response, but it is in essence, blaming externals for your course of illness and treatment and denial of your own agency in the process. This passive denial approach to disease and illness management was in many ways, considered appropriate and a normal adjustment as few as 25 years ago. The older medical model of ‘compliance,’ inferring that the healing professional knows everything and the patient (victim of the disease or accident) must only listen and follow directions in order to heal and become whole again, was a largely accepted viewpoint in medicine for many, many years.  We now know that for most patients, the best approach to disease management involves ‘adherence’ to the treatment plan. 

Adherence involves the patient actively learning, discussing and contributing to decision making with his/her health professional.   As a result, research shows that for most, this leads to higher motivation and better success in managing their disease.   For example, if diabetes management is your issue, then together with the health care professional, you establish your goals, how you’re going to achieve them and how long you will take to meet each objective.  Having this kind of agency and ownership of your treatment plan will help you overcome feelings of anger and be successful in the long run. So then, what is one of the best ways to overcome feeling victimized?   Become an active patient, willing to learn new things, ask questions, speak up about your denial, fears and your hopes and work together with your health care professional to improve your health and your wellbeing.